Als Tochtergesellschaft von CPEG stehen Ihnen zusätzliche Anlagen zur thermischen und Trockenverarbeitung sowie zur Materialhandhabung zur Verfügung, mit denen Sie Ihre Produktionslinie ergänzen und ausbauen können.

Kalzinatoren, Mischer, Vibrationsfließbetten, Schlauchfilter und vieles mehr.

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Pharmazeutisch

Buflovak unterstützt Pharmahersteller mit präzisionsgefertigten Trocknungs- und Verarbeitungsanlagen, die den strengen Industriestandards für Sauberkeit, Konsistenz und Validierung entsprechen. Unsere Vakuumtrockner und Verdampfer sind ideal für empfindliche Verbindungen und ermöglichen eine kontrollierte Verarbeitung bei niedrigen Temperaturen, um die Wirksamkeit des Produkts zu erhalten. Mit dem Fokus auf Zuverlässigkeit und Wiederholbarkeit hilft Buflovak Pharmaherstellern, Produktqualität, Reinheit und Prozesseffizienz sicherzustellen.

Maßgeschneiderte Ausrüstungslösungen

Atmosphärische Trommeltrockner

Vakuum-Doppeltrommeltrockner

Vakuum-Regaltrockner

Vakuum-Pfannentrockner

Vakuum-Rotationstrockner

Kühlwalzen-Flockenpressen

Verdampfung, Destillation und Trennung

Optimize Your Pharmaceutical Production Line When You Partner with Buflovak

Whether you’re developing a new API, scaling up a formulation, or modernizing an existing production line, Buflovak engineers collaborate directly with your team to design and deploy custom drying, evaporation, and crystallization systems tailored to your materials, solvents, throughput, and compliance requirements. With decades of experience, deep knowledge of thermal and vacuum processing, and flexible engineering discipline – we deliver solutions built for performance, purity, and reliability.

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Drying, Evaporation & Crystallization for Drug Manufacturing

The pharmaceutical sector demands the highest standards of purity, precision, and regulatory compliance. At Buflovak, we provide thermal drying, vacuum drying, evaporation, and crystallization systems purpose-built for the sensitive, high-value materials and processes typical in pharmaceutical manufacturing – from APIs to excipients and formulation intermediates.

Evaporation, Distillation & Separation Systems
Verdampfungskristallisatoren
Vakuum-Doppeltrommeltrockner
Vacuum Shelf & Pan Dryers
Kühlwalzen-Flockenpressen

Pharmaceutical Industry Pain Points We Solve

Degradation or potency loss from excessive heat during drying
Incomplete solvent removal or residual solvents in final product
Batch-to-batch inconsistency in moisture content or crystal form
Contamination risks due to open systems or poor sealing
High maintenance and cleaning burdens with legacy dryers
Inefficient solvent recovery, high energy consumption, or high solvent waste
Difficulty scaling from R&D to pilot to full production while retaining quality

Engineered for the Unique Demands of Pharmaceutical Production

Pharmaceutical materials – especially APIs and excipients often require drying under tightly controlled conditions to preserve potency, avoid degradation, and achieve required residual moisture levels. Buflovak’s equipment supports virtually every stage of pharmaceutical solids processing, including powder drying, measuring and blending flavors, drying agglomerates, and pre-tableting processes.

Drying

HPAPi’s – Pharmaceutical
API isolation, washing, & drying after synthesis or precipitation
Production of inhalable powders, granules, or bulk powders for tablets/capsules
Handling sterile or high-potency materials under controlled, closed systems
Powders & flavors
Agglomerates

Solids Processing

Filter cakes processing
Production of excipients, fillers, or co-processed excipients (e.g., lactose, salts, carriers)
Hygroscopic powders
High-viscosity slurries
Hygroscopic powders
Shear-sensitive materials – polymers, catalysts, emulsions, dispersions and more
Heat-sensitive compounds

Evaporation & Solvent Recovery

Solvent-heavy formulations used in APIs or excipients
Solvent recovery from reaction mixtures or wash streams
Solvent removal & recovery
High-viscosity solutions
Corrosive or reactive chemical intermediates
Fouling-prone streams where stable, continuous operation is needed
Solvent-containing slurries or cakes

Crystallization

High-purity crystalline APIs or intermediates
Controlled crystal size distribution and polymorphism
Solvent recovery or recycling during crystallization
Batch or continuous crystallization modes depending on volume and process needs

System Integration

Built for Your Process Ecosystem

Buflovak systems can be tailored to integrate seamlessly into existing production lines or new installations, ensuring optimal fit with:

Reactors / synthesis vessels
Filtration units (e.g., centrifuges, Nutsche filters)
Solvent recovery loops
Containment / isolation systems
Solvent recovery systems
Clean-in-place (CIP) or sterilization processes
Downstream milling, blending, or packaging systems

Advanced Evaporation & Solvent Recovery

Evaporation is often a critical step in chemical synthesis and formulation when concentrating solutions or removing solvents prior to isolation. Buflovak evaporation systems are engineered to handle a variety of materials.

These systems help enable efficient solvent removal or concentration before crystallization or drying, aligning with typical pharmaceutical process flows. 

Our evaporation portfolio includes:

Zwangsumlaufverdampfer
Film-type Evaporators (falling, rising film, etc.)
Plattenverdampfer
Continuous or batch configurations

Crystallization & Controlled Product Isolation

For many pharmaceutical products, the physical form (crystal size, polymorph, purity) is critical to performance, solubility, stability, and downstream processing.

Temperature & Solvent-Sensitive Processes

Vacuum crystallizers or jacketed crystallizers offer flexibility for temperature and solvent-sensitive processes – a common requirement in pharmaceutical manufacturing.

Why Pharmaceutical Manufacturers Choose Buflovak

Strict control over moisture, temperature, and atmosphere – critical for API stability, potency, and regulatory compliance.
Gentle drying for heat and solvent-sensitive materials through vacuum, indirect heating, or low-temperature technologies.
Closed-system processing to minimize contamination risk, support solvent recovery, and ensure operator safety.
Custom-engineered equipment designed to meet small batch (R&D/pilot) or large-scale production needs.
Hygienic, CIP-ready design when required – essential for cleanroom or sterile manufacturing environments.
Integrated evaporation and crystallization solutions for solvent removal, concentration, and controlled crystallization of active ingredients.

Benefits

Consistent, repeatable drying, crystallization, and concentration processes
High product purity and stability – essential for regulatory compliance
Lower total cost of ownership through energy-efficient designs and solvent recovery
Reduced risk of contamination thanks to closed, cleanable systems
Scalable solutions – from lab or pilot size to full-scale production
Reduced maintenance and downtime – especially important for high-value API production
Flexibility to handle a wide range of chemistries, solvents, viscosities, and processes

Technical Advantages

Buflovak systems can be configured with:

Vacuum or low-temperature drying for heat- or solvent-sensitive materials
Indirect heating to separate product from combustion gases or other contaminants
Solvent recovery / condensation systems for safe, efficient volatile handling
Closed-vessel crystallization to minimize contamination and control environment during supersaturation, nucleation, and growth phases
Agitated filter-dryer combinations or conical vacuum paddle dryers for combined isolation and drying of filter cakes
Clean-in-place (CIP) or sterile cleaning regimes for ease of maintenance and compliance

Frequently Asked Questions (FAQs)

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